In what will become one of the most talked about interviews of the year, Lance Armstrong has reportedly admitted to using performance enhancing drugs during his exclusive sit down with Oprah Winfrey on Monday.

According to CBS News, Oprah confirmed Lance’s admission during what she says is the “biggest interview” she’s ever done, after years of denial that he ever used performance enhancing drugs to win the Tour de France.

After the 2 1/2 hour interview, Oprah took to her Twitter to announce that she had just wrapped up with Lance.

Just wrapped with @lancearmstrong More than 2 1/2 hours . He came READY!

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Oprah Winfrey (@Oprah) January 14, 2013

Oprah appeared on CBS This Morning Tuesday to talk about what happened during the interview and her reaction. She told CBS This Morning that he “did not come clean in the manner that I expected,” adding “We were mesmerized and riveted by some of his answers” to her 112 prepared questions.

Listen to clips from CBS This Morning to hear what to expect in her anticipated interview below.

Because the interview contains so much, the entire sit down will broadcast in a two-night special starting Thursday on Oprah’s OWN channel. Watch the clip from CBS This Morning with Oprah below.